Preclinical PET Imaging Facility - Services & Equipment | Mallinckrodt Institute of Radiology - Washington University School of Medicine in St. Louis

Preclinical Imaging Facility

Scanners

Mediso nanoScan PET122S / CT1512 in vivo imager
Siemens Inveon MM PET/CT scanner
MR Solutions simultaneous PET/MR scanner
GE Typhoon FLA 9500 Biomolecular Imager
Perkin-Elmer Caliper IVIS Imager
C-arm portable X-ray imaging for large animals

Support Equipment

Macrotome for large tissue slicing
Leica 1860 Cryostat
Refrigerators and freezers
Gamma counters
Short-term animal housing for radioactive material (RAM) decay
Image-analysis station for facility users
Animal physiology monitoring equipment

Services & Studies

The facility provides investigators the tools and expertise to gather reliable and reproducible data in support of translational imaging and theranostic strategies.

Small animal CT imaging
Multi-modality PET-CT imaging
Simultaneous PET/MR imaging—enabling multi-parametric MR/PET and PET/MR spectroscopy
Bioluminescence imaging (BLI) of radioactive materials
Cerenkov imaging
Radio-bioluminescence imaging
Biodistribution studies
Radiation dosimetry for translation of imaging agents
Cell culture support (over 80 human and murine cell lines are available)
Surgical/technical procedures including administration of imaging agents, drugs, and tumor inoculation
Consultation on study design and protocol development
Project coordination with cyclotron, radiochemists, DCM housing, and other investigators
Image analysis/quantification (facility supported or collaboration depending on complexity)