Biomedical imaging plays a pivotal role in the diagnosis and staging of diseases, drug discovery, characterization and validation of novel biomarkers, and guiding disease management. Employing an interdisciplinary approach, the Sharma Lab designs and develops molecular imaging probes capable of interrogating important biochemical pathways across multiple disciplines. Although our research focus is not confined to any specific imaging modality, we frequently employ radiological molecular imaging for interrogating vital biochemical processes in cellulo and in vivo.
The lab, led by Vijay Sharma, PhD, works at the interface of chemistry, medicinal chemistry, radiopharmaceutical science, biochemistry and biology.
Our research focuses on employing state-of-the-art rational drug design tools. We are interested in the synthesis of small organic molecules, peptide conjugates and metalloprobes to interrogate important biological pathways and identify new biomarkers.