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Bennett Lab

Projects

Detecting Kidney Structure and Function at the Level of the Single Nephron

Goal

The goal of this longstanding project is to provide new tools to investigate the kidney, in vivo, at single-nephron resolution, and to provide translational tools to assess kidney health.

We use imaging tools including magnetic resonance imaging (MRI) and positron emission tomography (PET) to investigate kidney structure and physiology. This project has led to a variety of new discoveries, contrast agents, and software platforms for quantitative, three-dimensional assessment of the kidney.

  • NIH/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  • An STTR with XN Biotechnologies, Diabetes Research Center

Improving Kidney Transplant Allocation Through Noninvasive Imaging

Goal

The goal of this work is to develop noninvasive imaging tools to provide information to increase the number of donor kidneys available for transplantation. The Bennett Lab is investigating the use of radiological imaging to improve assessment of donor kidney health.

Multi-Scale Mapping of Gene Expression in the Kidney

We are developing techniques to investigate gene expression through single-cell RNA sequencing mapped throughout the entire organ based on radiological imaging.

Our People

Members of the Bennet Lab, along with physician collaborators, perform basic scientific investigations to bring new technologies to the clinic through translational studies.

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