Barry A. Siegel, MD
Professor of Radiology
Professor of Medicine
Clinical Expertise:Nuclear Medicine
Barry A. Siegel, MD, is a professor of radiology and of medicine at Washington University School of Medicine in St. Louis. Siegel served as senior vice chair and division director of nuclear medicine at the School of Medicine's Mallinckrodt Institute of Radiology (MIR) for over four decades before stepping down in 2017. During his tenure, he introduced clinical positron emission tomography (PET) services to the portfolio of activities offered in nuclear medicine. Siegel helped develop PET methods for imaging tumor receptors and hypoxia, and he assessed the utility of both conventional and novel PET agents in studying breast, prostate, cervical and other cancers. As associate principal investigator of the American College of Radiology (ACR) Imaging Network, Siegel helped guide a wide range of clinical trials of PET imaging, bridging the gap between clinicians and imaging specialists and elevating the quality of clinical trial conduct in imaging.
Through his work developing the National Oncologic PET Registry, he helped to greatly expand Medicare coverage for PET. More recently, he serves as co-chair of the Imaging Dementia—Evidence for Amyloid Scanning (IDEAS) Study, a national study designed to demonstrate the clinical value of brain amyloid PET in patients with mild cognitive impairment or dementia.
In 2021, Siegel received the ACR Gold Medal Award for his more than 40 years of leadership in the nuclear medicine community. The Gold Medal, the society's highest honor, recognizes his accomplishments in helping develop PET into a major clinical and research tool and elevating the quality of imaging clinical trials. Siegel is an alumnus of MIR’s diagnostic radiology residency and nuclear medicine fellowship programs, and he earned his undergraduate and medical degrees from Washington University.
nuclear medicine, nuclear imaging, PET, positron emission tomography, radioiodine treatment, radionuclide imaging
Positron emission tomography for cancer diagnosis and staging, and for predicting and monitoring response to cancer therapy
Link to Publications
American Medical Association
American College of Radiology
Missouri Radiological Society
Missouri State Medical Medical Association
Radiological Society of North America
St. Louis Metropolitan Medical Society
Society of Nuclear Medicine and Molecular Imaging
World Molecular Imaging Society