Researchers Investigate the Aging Brain in Multicenter Study

A functional MRI scan reveals the default mode network in the brain of a person at rest.

Researchers from Mallinckrodt Institute of Radiology (MIR) at Washington University School of Medicine in St. Louis are part of a multicenter team studying what keeps our brains sharp as we age thanks to a $33.1 million grant from the National Institute on Aging. The project, known as the Adult Aging Brain Connectome study, will follow 1,000 younger, middle-aged and older adults over several years in hopes of identifying factors that put people at risk for, or protect them from, cognitive decline.

Members of the team from MIR include Beau M. Ances, MD, PhD, the Daniel J. Brennan, MD, Professor of Neurology, who is a co-principal investigator; Matthew F. Glasser, PhD, a research fellow in radiology who leads the processing core; and Daniel S. Marcus, PhD, a professor of radiology who leads the informatics core.

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