Small-Animal Magnetic Resonance Facility

The Small Animal MR Facility includes a Bruker 9.4-T (400-MHz) MRI system, an Agilent/Varian DirectDrive 4.7-T (200-MHz) MRI system, and an Agilent/Varian DirectDrive 11.74-T (500-MHz) MRI system, all housed in on-grade adjoining suites.  The magnetic field strengths of BMRL scanners are substantially higher than generally encountered in clinical systems, typically 0.5 – 3.0 T.  Advantages of high field are chiefly related to signal-to-noise ratio gains, which translate into improved spatial or temporal resolution for imaging and improved accuracy of resonance amplitude and frequency estimates for spectroscopy.  Immediately adjacent to the MR scanner bays are animal holding and procedure rooms, a wet chemistry lab, an electronics lab and a climate-controlled room holding computer server and data archival devices.

The following links provide additional information about Small-Animal MR Facility resources:

MRI Scanners
RF Coils

Animal Procedure Support - The small-animal MR imaging suite includes a 200-sq-ft animal procedure room equipped with operating light and table. A full suite of MR-compatible (in-magnet) monitoring equipment is available to follow and assess animal physiology, including a ventilator/respiratory rate monitor with pressure sensing and hardware gating for precise respiratory gating. Three Small Animal Instruments, Inc. (Stony Brook, NY; USA) Model 1025 MR-compatible Small Animal Monitoring and Gating Systems are also available, capable of measuring and recording ECG, respiration, temperature, and invasive blood pressure.

Across the hall from the surgical suite are two dedicated, specially-designed, 150-sq-ft holding rooms for animals. These small-animal quarters are managed by the Division of Comparative Medicine. The University also maintains state-of-the-art barrier and non-barrier animal facilities immediately across the street. A modern histology facility, outfitted with equipment for intracardiac animal perfusion, embedding brain tissue in paraffin or plastic, tissue sectioning, tissue staining, and histologic analysis (either by electron microscope, light microscope or computer-aided image analysis) is also located nearby.

Wet Chemistry and Electronic Support
Computers, Data Storage, and Internet
Computational Software
Data Archival and Backup

Apply for MIR Pilot Studies Funding

Small-Animal MR Imaging Facility Scheduler