The goals of each project will be to develop PET radiotracers that will image biologic targets modulating the ubiquitous disease processes of inflammation, oxidative stress and angiogenesis.
The Co-Leaders of each TR&D are:
Zhude Tu and Delphine Chen - Project 1: Imaging Sphingosine-1-Phosphate Receptor 1 (S1P1)
Yongjian Liu and Robert Gropler - Project 2: Imaging of Chemokine Receptors
Vijay Sharma and Kooresh Shoghi - Project 3: Imaging of iNOS and ROS/RNS
The TR&Ds will also conduct scale-up synthesis in order to provide the necessary materials (e.g., precursors and HPLC standards) to the Collaborative and Service Projects.