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Radiological Chemistry and Imaging Laboratory (RCIL)

David Reichert

Contact Information
Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

Office:
4420 Clinical Sciences Research Building
(314) 362-8461
reichertd@mir.wustl.edu

Current Position
Associate Professor of Radiology
 

Research Interests
My research focuses on the development of novel imaging agents and tools for the design and preparation of radiopharmaceuticals. This involves many areas of chemistry ranging from organic synthesis to computer modelling and development of microfluidic devices.

  • Computer aided design of radiopharmaceuticals
  • Cellular and molecular actions of neuroactive steroids
  • Microfluidic radiometal labeling of biomolecules
  • The use of in vivo imaging to study immune function
     

Key Publications:

  1. Triazine-based tool box for developing peptidic PET imaging probes: Syntheses, microfluidic radiolabeling, and structure-activity evaluation. Hairong Li, Haiying Zhou, Stephanie Krieger, Jesse J. Parry, Joseph J. Whittenberg, Amit V. Desai, Buck E. Rogers, Paul J. A. Kenis, David E. Reichert, Bioconjug Chem. 25(4):761-72, 2014..
  2. Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABAA receptor. Zi-Wei Chen, Brad Manion, R Reid Townsend, David E Reichert, Douglas F Covey, Joe Henry Steinbach, Werner Sieghart, Karoline Fuchs, Alex S Evers, Mol Pharmacol, 82(3):408-19, 2012.
  3. Microfluidic labeling of biomolecules with radiometals for use in nuclear medicine. Tobias D Wheeler, Dexing Zeng, Amit V Desai, Birce Onal, David E Reichert, Paul J A Kenis, Lab Chip, 10(24):3387-96, 2010
  4. Subtype selectivity of dopamine receptor ligands: Insights from structure and ligand-based methods. Qi Wang, Robert H Mach, Robert R Luedtke, David E Reichert, J Chem Inf Model, 50(11):1970-85, 2010.
  5. QSAR studies of copper azamacrocycles and thiosemicarbazones: MM3 parameter development and prediction of biological properties. Peter Wolohan, Jeongsoo Yoo, Michael J Welch, David E Reichert, J Med Chem, 48(17):5561-9, 2005.