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Radiological Chemistry and Imaging Laboratory (RCIL)

Hongjun Jin 

Contact Information
Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

Office:
254B McDonnell Medical Sciences Building
(314) 362-0754
hongjunj@mir.wustl.edu

Current Position
Instructor in Radiology
 

Research Interests
My research focuses on biochemically characterization of radiotracers for CNS and oncology molecular imaging.

  • Early detection of breast cancer using post-translationally modified biomarkers
  • Characterization of radiotracers for VAChT and PDE10A
  • Molecular imaging and kinetics studies for tracers developed by Dr. Tu’s research group
     

Key Publications:

  1. Zhang X, Jin H, Padakanti PK, Li J, Yang H, Fan F, Mach RH, Kotzbauer P and Tu Z Radiosynthesis and in vivo evaluation of two PET radioligands for imaging α-synuclein. Appl. Sci. 4(1): 66-78; 2014.
  2. Jin H, Halstrand TS, Daly DS, Matzke MM, Nair P, Bigelow DJ, Pounds JG and RC Zangar. A halotyrosine antibody that detects increased protein modifications in asthma patients. J Immunol Methods, 403:17–25, 2014. PMID:24295867.
  3. Jin H, Xu M, Padakanti PK, Liu Y, Lapi S, Tu Z. (2013) Preclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging. Mol Pharm. 10(10): 3655–3664, 2013. PMID:23964702.
  4. Li J, Zhang X, Zhang Z, Padakanti PK, Jin H, Cui J, Li A, Zeng D, Rath NP, Flores H, Perlmutter JS, Parsons SM, Tu Z. (2013). Heteroaromatic and aniline derivatives of piperidines as potent ligands for vesicular acetylcholine transporter. J Med Chem. 5(15): 6216-33. PMID:23802889.
  5. Li J, Jin H, Zhou H, Rothfuss J, Tu Z. (2013) Synthesis and bioactive evaluation of pyrazole group-containing analogues for PDE10A. MedChemComm. 4(2): 443–449. PMID:23585921