Precision Radio-Theranostics Translational Laboratories (PRT2L)

Yuan-Chuan Tai

Contact Information

Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

4402B  Clinical Sciences Research Building
(314) 362-8429

Current Position
Associate Professor of Radiology, Biomedical Engineering, Electrical and Systems Engineering

Research Interests
My research focuses on the development of novel molecular imaging systems and technologies for clinical, preclinical and plant imaging applications.

  • Augmented Whole-body Scanning via Magnifying PET (AWSM-PET) technology to improve the accuracy of clinical PET/CT for cancer detection
  • A compact PET/ultrasound imager for interactive point-of-care PET/US imaging
  • Molecular and functional plant imaging
  • Image-guided radio-theranostics

Key Publications: 

  1. Jiang J, Samanta S, Li K, Siegel SB, Mintzer RA, Cho S, Conti M, Schmand M, O'Sullivan J, Tai YC. Augmented Whole-Body Scanning via Magnifying PET. IEEE Trans Med Imaging. 2020 Nov; 39(11):3268-3277. PMID: 31899415. PMCID: PMC7673659. doi: 10.1109/TMI.2019.2962623. 
  2. Jiang J, Li K, Komarov S, O'Sullivan JA, Tai YC. Feasibility study of a point-of-care positron emission tomography system with interactive imaging capability. Med Phys. 2019 Apr; 46(4):1798-1813. PMID: 30667069. PMCID: PMC6453727. doi: 10.1002/mp.13397. 
  3. Jiang J, Li K, Wang Q, Puterbaugh K, Young JW, Siegel SB, O'Sullivan JA, Tai YC. A second-generation virtual-pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole-body PET/CT scanner. Med Phys. 2019 Sep; 46(9):4165-4176.  PMID: 31315157; PMCID: PMC6739194. doi: 10.1002/mp.13724. 
  4. Mathews AJ, Li K, Komarov S, Wang Q, Ravindranath B, O'Sullivan JA, Tai YC. A generalized reconstruction framework for unconventional PET systems. Med Phys. 2015 Aug; 42(8):4591-4609. PMID: 26233187. PMCID: PMC4506302. doi: 10.1118/1.4923180. 
  5. Wang Q, Mathews AJ, Li K, Wen J, Komarov S, O'Sullivan JA, Tai YC. A dedicated high-resolution PET imager for plant sciences. Phys Med Biol. 2014 Oct 7; 59(19):5613-5629. PMID: 25190198. doi: 10.1088/0031-9155/59/19/5613.