Precision Radio-Theranostics Translational Laboratories (PRT2L)

Yuan-Chuan Tai

Contact Information
Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

4402C Clinical Sciences Research Building
(314) 362-8429

Current Position
Associate Professor of Radiology and Biomedical Engineering


Research Interests
My research focuses on the development of novel molecular imaging systems and technologies for clinical, preclinical and plant imaging applications.

  • Virtual-pinhole PET (VP-PET) technology for high-resolution human imaging applications
  • Sub-millimeter resolution PET for preclinical imaging application
  • Molecular and functional plant imaging
  • High resolution Cherenkov imaging

Key Publications: 

  1. Ranjbar H, Wen J, Mathews AJ, Komarov S, Wang Q, Li K, O'Sullivan JA, Tai YC. (2016) A simultaneous beta and coincidence-gamma imaging system for plant leaves. Phys Med Biol. 61(9):3572-95.
  2. Mathews AJ, Li K, Komarov S, Wang Q, Ravindranath B, O'Sullivan JA, Tai YC. (2015) A generalized reconstruction framework for unconventional PET systems. Med Phys. 42(8):4591-609. PMCID: PMC450630.
  3. Komarov S, Zhou D, Liu Y, Tai YC. (2015) Cherenkov luminescence imaging in transparent media and the imaging of thin or shallow sources. J Biomed Opt. 20(3):36011. PMCID: 4365802.
  4. Wang Q, Mathews AJ, Li K, Wen J, Komarov S, O'Sullivan JA, Tai YC. (2014) A dedicated high-resolution PET imager for plant sciences. Phys Med Biol. 59(19):5613-29.
  5. Mathews AJ, Komarov S, Wu H, O'Sullivan JA, Tai Y-C. (2013) Improving PET imaging for breast cancer using virtual pinhole PET half-ring insert. Phys Med Biol. 58(18):6407-27. PMCID: 3890243.