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Precision Radio-Theranostics Translational Laboratories (PRT2L)

Yongjian Liu

Contact Information
Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

Office: 
4402C Clinical Sciences Research Building
(314) 362-8431
liuyo@mir.wustl.edu
 

Current Position
Associate Professor of Radiology
 

Research Interests
My research focuses on the development of novel molecular probes for preclinical and translational imaging and therapy.

  • Development of nanoparticle based agents for pre-clinical imaging and therapy
  • Preparation of small molecule and peptide agents for PET imaging
  • Assessment of Cherenkov imaging for biomedical applications
  • GMP production of biomolecules for translational research
     

Key Publications:

  1. Mahmoud Elsabahy, Ang Li, Fuwu Zhang, Deborah Sultan, Yongjian Liu, Karen L. Wooley. Differential immunotoxicities of poly(ethylene glycol) vs. poly(carboxybetaine)-coated nanoparticles. J Controlled Release, 172: 641-652, 2013. PMID: 24056145
  2. Yucai Wang, Kvar C.L. Black, Hannah Luehmann, Weiyang Li, Yu Zhang, Xin Cai, Dehui Wan, Si-Yun Liu, Max Li, Paul Kim, Zhi-Yuan Li, Lihong V. Wang, Yongjian Liu, Younan Xia.  Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. ACS Nano, 7: 2068-2077, 2013.
  3. Yongfeng Zhao, Deborah Sultan, Lisa Detering, Sangho Cho, Guorong Sun, Richard Pierce, Karen L. Wooley, Yongjian Liu. Copper-64-alloyed gold nanoparticles for cancer imaging: Improved radiolabel stability and diagnostic accuracy. Angewandte Chemie International Edition. 53: 156-159, 2014.
  4. Hannah P. Luehmann, Eric D. Pressly, Lisa Detering, Cynthia Wang, Richard Pierce, Pamela K. Woodard, Robert J. Gropler, Craig J. Hawker, Yongjian Liu. PET/CT Imaging of chemokine receptor CCR5 in vascular injury model using targeted nanoparticle. J Nuc Med, 55: 629-634, 2014.
  5. Kvar C. Black, Yucai Wang, Hannah P. Luehmann, Xin Cai, Wenxin Xing, Bo Pang, Yongfeng Zhao, Cathy S. Cutler, Lihong V. Wang, Yongjian Liu, Younan Xia. Radioactive 198Au-doped nanostructures with different shapes for in vivo analyses of their biodistribution, tumor uptake, and intratumoral distribution. ACS Nano, 8: 4385-4394, 2014.