Precision Radio-Theranostics Translational Laboratories (PRT2L)


Richard Laforest

Contact Information
Washington University School of Medicine
Department of Radiology
Campus Box 8225
510 S. Kingshighway
St. Louis, MO 63110

1017F Mallinckrodt Institute of Radiology
(314) 362-8423

Current Position
Professor of Radiology
Co-Director, Small Animal Cancer Imaging Core, Siteman Cancer Center
Co-Director, Preclinical PET/CT Imaging Facility
Nuclear Medicine Medical Physicist Barnes-Jewish Hospital

Research Interests
My research focuses on the development of image reconstruction, data evaluation and data analysis tools for clinical and preclinical imaging applications.

  • High-resolution PET imaging
  • Motion correction for PET
  • Multimodality imaging PET/CT/MR

Key Publications:

  1. Maughan NM, Eldib M, Conti M, Knesaurek K, Faul D, Parikh P, Fayed Z, Laforest R. Phantom study to determine optimal PET reconstruction parameters for PET/MR imaging of  90Y microspheres following radioembolization.  Biomed Phys Eng Express. 2016 Feb 4; 2(1):e015009. doi:10.1088/2057-1976/2/1/015009.
  2. Cheng JCK, Boellaard R, Laforest R. Evaluation of the effect of magnetic field on PET spatial resolution and contrast recovery using clinical PET scanners and EGSnrc simulations.  IEEE Trans Nucl Sci. 2015 Feb; 62(1):101-110. doi: 10.1109/TNS.2014.2373147.
  3. Lau JM, Laforest R, Sotoudeh H, Nie X, Sharma S, McConathy J, Novak E, Priatna A, Gropler RJ, Woodard PK. Evaluation of attenuation correction in cardiac PET using PET/MR.  J Nucl Cardiol. 2017 Jun; 24(3):839-846. Epub 2015 Oct 23. PMID: 26499770. PMCID: PMC6360086. doi: 10.1007/s12350-015-0197-1.
  4. Dehdashti F, Laforest R, Gao F, Shoghi KI, Aft RL, Nussenbaum B, Kreisel FH, Bartlett NL, Cashen A, Wagner-Johnston N, Mach RH. Assessment of cellular proliferation in tumors by PET using  18F-ISO-1. J Nucl Med. 2013 Mar; 54(3):350-7. PMID: 23359657. PMCID: 3694753. doi:10.2967/jnumed.112.111948.
  5. Goertzen AL, Bao Q, Bergeron M, Blankemeyer E, Blinder S, Canadas M, Chatziioannou AF, Dinelle K, Elhami E, Jans HS, Lage E, Lecomte R, Sossi V, Surti S, Tai YC, Vaquero JJ, Vicente E, Williams DA, Laforest R. NEMA NU 4-2008 comparison of preclinical PET imaging systems.  J Nucl Med. 2012 Aug; 53(8):1300-1309. PMID: 22699999. PMCID: 4128012. doi: 10.2967/jnumed.111.099382.