Berezin Research Group - Publications - Peer-Reviewed

Peer-Reviewed Publications


63. Cui M, Binkley M, Shekhani H, Berezin, MY, and Meacham JM*, Augmented longitudinal acoustic trap for scalable microparticle enrichment, Biomicrofluidics, 2018 (accepted May 30, 2018)

62. Lin L-Y, Kavadiya S, Karakocak BB, Nie Y, Raliya R, Wang ST, Berezin MY, Biswas P, ZnO1-x/Carbon Dots Composite Hollow Spheres: Facile Aerosol Synthesis and Superior CO2 Photoreduction under UV, Visible and Near-Infrared Irradiation, Applied Catalysis B:  Environmental  2018, 230, 36-48


61. Miller J, Wang ST, Orukari I, Prior J, Sudlow G, Su X, Liang K, Tang R, Hillman EMC, Weilbaecher KN, Culver J, Berezin MY, Achilefu S*, Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near infrared molecular probes, J Biophotonics2017 accepted, DOI: 10.1002/jbio.201700232)

60. Cheadle C, Ratcliff J, Berezin MY*, Palshin V, Nemykin V, Gerasimchuk N*,  Shortwave infrared luminescent Pt-nanowires: mechanistic study of emission in solution and solid state, Dalton Transactions2017, 46, 13562-13581

59. Thimsen E, Sadtler B, Berezin, MY,* Shortwave-infrared (SWIR) emitters for biological imaging: a review of challenges and opportunities, Nanophotonics2017 6(5): 1043–1054 (link)

58.  Dysli C, Wolf S, Berezin MY, Sauer L, Hammer M, Zinkernagel M, Fluorescence Lifetime Imaging Ophthalmoscopy, Progress in Retinal and Eye Research2017 60, 120-143 (link)

57.  Zhou H, Tourkakis G, Shi D, Kim DM, Zhang H, Du T, Eades WC, Berezin MY,* Cell-free measurements of brightness of fluorescently labeled antibodies, Scientific reports, 2017, 7, 41819

56. Thi  HL, Zhou H, Lin C_H, Liu S, Berezin MY, Smeda RJ, and Fritschi FB, Synthesis and plant growth inhibitory activity of N-trans-cinnamoyltyramine - Its possible inhibition mechanisms and biosynthesis pathway, Journal of Plant Interactions, 2017, 12, 51-57


55. Zhang H, Salo D, Kim D, Komarov S, Tai Y-C, Berezin MY,* Penetration depth of photons in biological tissues from hyperspectral imaging in SWIR in transmission and reflection geometries, J. Biomed. Optics, 2016, 21(12), 126006
54. Zhou H, Yang Y, Ee X, Hunter DA, Akers WJ, Wood MD, Berezin MY,* Imaging of radicals following injury or acute stress in peripheral nerves with activatable fluorescent probes, Free Radical Biology & Medicine, 2016, 101, 85–92
53. Yin B, Sadtler B, Berezin MY, and Thimsen E, Quantum dots protected from oxidative attack using alumina shells synthesized by atomic layer deposition, Chem. Commun, 2016, 52, 11127-11130
52. Black KC, Ibricevic A, Gunsten SP, Flores JA, Gustafson TP, Raymond J, Samarajeewa S, Shrestha R, Felder S, Cai T, Shen Y, Löebs A, Zhegalova N, Sultan DH, Berezin MY, Taylor J-S, Wooley K, Liu Y, Brody S. In vivo fate tracking of degradable nanoparticles for lung gene transfer using PET and Ĉerenkov imaging, Biomaterials, 2016, 98, 53–63
51. He S, Tourkakis G, Berezin OY, Gerasimchuk N, Zhang H, Israely A, Zhou H, Akers W, Berezin MY* Temperature-dependent shape-responsive fluorescent nanospheres for image-guided drug delivery, J. Mater. Chem. C, 2016, 4, 3028-3035
50. Zhou H, Sharma M, Berezin O, Zuckerman D, Berezin MY,* Nanothermometry: from microscopy to thermal treatments, ChemPhysChem, 2016, 17(1):27-36 (VIP paper)


49. Zhang H, Wu Q, Berezin MY,* Fluorescence anisotropy (polarization): from drug screening to precision medicine, Expert Opinion on Drug Discovery, 2015, 10(11):1145-61
48. Kim DM, Zhang H, Zhou H, Du T, Wu Q., Mockler T, Berezin MY,* Highly sensitive image-derived indices of water-stressed plants using hyperspectral imaging in SWIR and histogram analysis, Scientific Reports, 2015, 5, Article number: 15919 (2015)
47. Zhou H, Gunsten SP, Zhegalova NG, Bloch S, Achilefu S, Holley JC, Schweppe D, Akers W, Brody SL, Eades WC, Berezin MY,* Visualization of Pulmonary Clearance Mechanisms via Noninvasive Optical Imaging Validated by Near-Infrared Flow Cytometry, Cytometry A, 2015, 87(5):419-27
46. Klaus D,  Keene M, Silchenko S, Berezin MY,* Gerasimchuk N, 1D polymeric Pt cyanoximate: a strategy toward luminescence in the near-infrared region beyond 1000 nm, Inorganic Chemistry, 2015, 54 (4), pp 1890–1900


45.  Salo D, Zhang H, Kim D, Berezin MY*, Multispectral measurement of contrast in tissue-mimicking phantoms in near-infrared spectral range 650-1600 nm, 2014, J. Biomed. Optics, 2014, 19(8), 086008
44.  Zhegalova NG, Dergunov SA, Wang ST, Pinkhassik E, Berezin MY*, Design of fluorescent nanocapsules as ratiometric nanothermometers, Chemistry – Eur. J., 2014, 20(33), 10292-10297 (featured on the cover)
43.  Zhegalova NG, He S, Zhou H, Kim DM, Berezin MY*, Minimization of self-quenching fluorescence on dyes conjugated to biomolecules with multiple labeling sites via asymmetrically charged NIR fluorophores, Contrast Media & Molecular Imaging, 2014, 9 (5), 355–362
42.  Krupnick AS, Lin X, Li W, Higashikubo R, Zinselmeyer B, Hartzler H, Toth K, Ritter J, Berezin MY, Wang, S, Gelman A, Kreisel D, Ccr7+Cd8+ Central memory T lymphocytes mediate lung alograft acceptance through IFN-γ dependent nitric oxide production, J. Clin. Invest., 2014;124(3):1130–1143 (pdf version)


41. Zhegalova NG, Gonzales G., Berezin MY*, Synthesis of nitric oxide probes with fluorescence lifetime sensitivity, Org. Biomol. Chem., 2013, 11 (47), 8228 – 8234 (pdf version)
40. Cao Q, Zhegalova NG, Wang ST, Akers WJ, Berezin MY*, Multi-spectral imaging in the extended NIR window based on endogenous chromophores, J. Biomed. Optics, 2013, 18(1), 016013
39. Mathieu L, Viger ML, Sheng W, McFearin CL, Berezin MY, Almutairi A, Application of time-resolved fluorescence for direct and continuous probing of release from polymeric delivery vehicles, J. Control. Release, 2013, 171(3), 308–314
38. Wang ST, Zhegalova NG, Gustafson TP, Zhou, A., Sher, J, Achilefu S., Berezin, OY., Berezin MY*., Sensitivity of activatable ROS probes by fluorescence spectroelectrochemistry, Analyst, 2013, 138, 4363-4369 (pdf version)
37. Gustafson TP, Dergunov SA, Akers WJ, Cao Q, Magalotti S, Achilefu S, Pinkhassik E, Berezin MY*, Blood triggered rapid release porous nanocapsules, RCS Advances, 2013, 3, 5547-5555 (pdf version)
36. Magalotti S, Gustafson TP, Cao Q, Abendschein D, Pierce R, Berezin MY*, Akers WJ, Evaluation of inflammatory response to acute ischemia using near-infrared fluorescent reactive oxygen sensors, Mol. Imaging Biol, 2013, 15 (4), 423-430 (pdf version)
35. Gustafson TP, Cao Q, Wang, S. Berezin MY*, Design of irreversible optical nanothermometers for thermal ablations, Chem. Commun., 2013, 49, 680-682 (pdf version)
34. Lee H, Berezin MY, Tang R, Zhegalova N, Achilefu S, Pyrazole-substituted near-infrared cyanine dyes exhibit pH dependent fluorescence lifetime properties, Photochem.  Photobiol, 2013, 89 (2), 326–331 (pdf version)


33. Gustafson TP, Yan P, Newton P, Hunter DA, Achilefu S, Akers WJ, Mackinnon SE, Johnson PJ, Berezin MY,* A NIR dye for development of peripheral nerve targeted probes, Med.Chem.Commun, 2012, 3, 685-690 (featured on the cover) (pdf version)
32. Gustafson TP, Cao Q, Achilefu S, Berezin MY*, Defining a polymethine dye for fluorescence anisotropy applications in the NIR spectral range, ChemPhysChem, 2012, 13(3), 716-23 (VIP paper) (pdf version)
31. Guo K, Achilefu S, Berezin MY*, Dating Bloodstains with Fluorescence Lifetime Measurements, Chemistry, - Eur. J., 2012, 18(5) 1303-1305 (pdf version)


30. Berezin MY,* Zhan C, Lee H, Joo C, Akers WJ, Yazdanfar, S, Achilefu S. Two-photon optical properties of near-infrared dyes at 1.55 μm excitation. J. Phys. Chem. B., 2011, 115(39):11530-5
29. Solomon M, Guo K, Sudlow G., Berezin MY, Edwards W, Achilefu S, Akers W, Detection of enzyme activity in orthotopic murine breast cancer by fluorescence lifetime imaging using a fluorescence resonance energy transfer–based molecular probe, J. Biomed. Optics, 2011, 16(6)
28. Solomon M, Liu Y, Berezin MY, Achilefu S. Optical Imaging in Cancer Research: Basic Principles, Tumor Detection, and Therapeutic Monitoring, Medical Principles and Practice, 2011, 20(5):397-415
27. Berezin MY, Guo K, Akers W, Nothdurft RE, Culver JP, Teng B, Vasalatiy O, Barbacow K, Gandjbakhche A, Griffiths GL, Achilefu S, Near-Infrared Fluorescence Lifetime pH-Sensitive Probes. Biophys. J., 2011, 20; 100(8):2063-72
26. Liu Y, Bauer AQ, Akers WJ, Sudlow G, Liang K, Shen D, Berezin MY, Culver JP, Achilefu S, Hands-free, wireless goggles for near-infrared fluorescence and real-time image-guided surgery, Surgery, 2011, 149(5):689-98
25. Berezin MY, Guo K, Akers W, Livingston J, Solomon M, Lee H, Liang K, Agee A. Achilefu S., Rational approach to select small peptide molecular probes labeled with fluorescent cyanine labels dyes for in vivo optical imaging, Biochemistry, 2011; 50(13):2691-700
24. Akers W, Kim C, Berezin MY, Guo K, Fuhrhop R, Lanza G, Fischer G, Daltrozzo E, Zumbusch A, Cai X, Wang L, Achilefu S, Non-invasive photoacoustic and fluorescence sentinel lymph node identification using dye-loaded perfluorocarbon nanoparticles, ACS Nano, 2011, 5(1),173-82


23. Chen R, Parry J, Akers W, Berezin MY, El Naqal I, Achilefu S, Edwards B, Rogers B. Multimodality imaging of gene transfer using a receptor-based reporter gene, J. Nucl. Med., 2010, 51, (9) 1456-1463
22. Yazdanfar S, Joo C, Zhan C, Berezin MY, Akers W, Ye Y, Achilefu S. Multiphoton microscopy of near-infrared contrast agents, J. Biomed. Optics, 2010, 15, 030505
21. Guo K, Berezin MY, Zheng J, Akers W, Lin F, Teng B, Vasalatiy O, Gandjbakhche, A., Griffiths, G. L., Achilefu S. Near-infrared fluorescent and magnetic resonance imaging molecular probe with high T(1) relaxivity for in vivo multimodal imaging. Chem. Commun., 2010, 46, 3705-3707
20. Berezin MY*, Achilefu S. Fluorescence lifetime measurements and biological imaging, Chem. Rev., 2010, 110 (5), 2641–2684 (more than 740 citations)
19. Akers W, Zhang Z, Fuhrhop R, Berezin MY, Ye, Y., Agee A, Guo K, Lanza, G, Achilefu S. Targeting of ανβ3-Integrins expressed on tumor tissue and neovasculature using fluorescent small molecules and nanoparticles, Nanomedicine, 2010, 5 (5), 715-26
18. Sun G, Berezin MY*, Fan J, Lee H, Zhang K, Achilefu S, Wooley K, Bright Fluorescent Nanoparticles for Developing of Potential Optical Imaging Contrast Agents, Nanoscale, 2010, 2, 548-558


17. Berezin MY, Akers W, Guo K, Fischer GM, Daltrozzo E, Zumbusch A, Achilefu S, Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging, Biophys. J., 2009, 97, L22-L24
16. Berezin MY, Guo K, Teng B, Edwards W, Anderson C, Vasalatiy O, Gandjbakhche A, Griffiths G, Achilefu S. Radioactivity synchronized fluorescence enhancement using a radionuclide fluorescence-quenched dye J. Am. Chem. Soc., 2009, 131(26): 9198-200. Featured in Science: J. Yeston, Nuclear glow, (editorial choice), 2009, 324, 1619-1621
15. Goiffon R, Akers W, Berezin MY, Lee H, Achilefu S, Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging J. Biomed. Optics, 2009, 14 (2), 020501-3
14. Zhang Z, Fan, J, Cheney P, Berezin MY, Akers W, Shen D, Edwards W, Culver J, Achilefu S, Homologous donor-acceptor near-infrared FRET system for monitoring enzyme activities Mol. Pharmaceutics, 2009,

6(2) 416-2

13. Berezin MY, Kao J, Achilefu S. pH-Dependent optical properties of synthetic fluorescent imidazoles Chemistry - Eur. J., 2009, 15(14), 3560-6
12. Lee H,  Berezin MY, Guo K, Kao J, Achilefu S. Near-infrared pH-fluorescent probes via unexpected barbituric acid mediated synthesis Org. Lett., 2009, 11(1), 29-32


11. Almutairi A, Akers W, Berezin MY, Achilefu S, Frechet JM, Monitoring the biodegradation of dendritic near infrared nanoprobes by in vivo fluorescence imaging. Mol. Pharmaceutics, 2008, 5 (6) 1103-1110
10. Lee H, Berezin MY, Henary M, Strekowski L, Achilefu S. Fluorescence lifetime properties of near-infrared cyanine dyes in relation to their structures J. Photochem Photobiol. A: Chemistry, 2008

, 200, 438-44

9. Akers W, Berezin MY, Lee H, Achilefu S. Predicting in vivo fluorescence lifetime behavior of NIR fluorescent contrast agents using in vitro measurements, J. Biomed. Optics, 2008, 13(5), 0540421-9
8. Almutairi A, Guillaudeu SJ, Berezin MY, Achilefu S, Frechet JM. Biodegradable pH-Sensing dendritic nanoprobes for near-infrared fluorescence lifetime and intensity imaging. J. Am. Chem. Soc., 2008; 130(2),  444-445
7. Zhang Z, Berezin MY, Kao J., d’Avignon, A, Achilefu S. Near-Infrared dichromic fluorescent carbocyanine molecules. Angew. Chem. Int. Ed. Engl. 2008; 47(19) 3584-7

2007 and before 

6. Berezin MY, Lee H, Akers W, Achilefu S, Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems. Biophys. J., 2007, 93, 2892-2899
5. Berezin MY, Lee H, Akers W, Nikiforovich G, Achilefu S., Ratiometric analysis of fluorescence lifetime for probing binding sites in albumin with near infrared fluorescent molecular probes. Photochem. Photobiol.,2007, 83, 1-8
4. Berezin MY, Achilefu S, Novel synthon for incorporating 1,3-dimethyl-imidazolium group into molecular architecture. Tetrahedron Lett., 2007, 48(7), 1195-1199
3. Zhang Z, Liang K, Bloch S, Berezin MY, Achilefu S, Monomolecular multimodal fluorescence-radioisotope imaging agentsBioconjug. Chem., 2005, 16(5), 1232-1239
2. Berezin MY*, Dzenitis JM, Hughes BM, Ho SV, Separation of Sterols Using Zeolites. Phys. Chem., Chem. Phys,. 2001

, 3, 2184-218

1. Berezin M, Wan K.-T, Friedman RM, Orth RG, Raman SN., Ho SV, Ebner JR , Thiol Protected Platinum Black and Palladium Black Catalysts in Oxidation CatalysisJ. Mol. Catal. A. Chem. 2000, 158(2), 567-576