Postdoctoral Research Associate (PRTC, Ribeiro Pereira Lab)
The Ribeiro Pereira Lab is a preclinical multimodal imaging laboratory that aims at modulating the availability of surface targets by elucidating their regulatory mechanisms to enhance antibody and non-antibody based tumor therapies. The research program has four major goals:
• Use biomolecules as tumor-targeting agents to deliver imaging or cytotoxic cargo.
• Use multimodal imaging to monitor the binding of molecular-targeted compounds to tumors before and during therapy.
• Use genetic and temporal pharmacologic approaches to modulate tumor biology in ways that enhance tumor binding of antibody- and non-antibody-based cancer therapies.
• Improve cancer diagnosis and treatment by combining basic tumor biology with preclinical knowledge and clinical needs.
The applicant will work under the supervision of Dr. Patrícia Ribeiro Pereira, PhD.
Visit this page on the Office of Postdoctoral Affairs website for information on being a postdoc at Washington University in St. Louis.
Primary Duties & Responsibilities
Training under the supervision of faculty mentors, including (but not limited to):
• Works with cell lines, fresh cultures of tumors, and patient-derived xenografts.
• Develops radiolabeled biomolecules and cell labeling technologies, dosimetry, and pharmacodynamics/pharmacokinetics studies.
• Correlates molecular imaging findings with the respective tumor’s genetic profile.
• Modulates tumor biology by using genetically modified mouse models and pharmacologic approaches.
• Uses multimodal imaging to visualize cancer-immune cell interaction.
• Converts novel scientific ideas to hypothesis-driven scientific experiments.
• Designs and conducts experimental methods while critically interpreting experimental results.
• Presents research findings to a multidisciplinary audience.
Ph.D., M.D. or equivalent terminal or doctoral degree.
• PhD in chemistry, biochemistry, or a related field to help achieve the four primary goals of our research program.
• Expertise in tumor biology or oncology is highly desirable.
• Background in pharmacology, biochemistry, or immuno-oncology.
• Enthusiastic and motivated with good verbal and written communication skills.
• Strong interest in our research program and laboratory environment.
• Fearless to learn new techniques, design research projects independently, and willing to prepare grants and manuscripts.
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and provide standard care to research animals.
Base pay commensurate with experience.
Applicant Special Instructions
Please send a CV with contact information of references and a cover letter (describing relevant expertise and scientific interests) to Dr. Patrícia Ribeiro Pereira, PhD, at .