Postdoctoral Research Associate (NIL-RC, Gordon Lab)

Position Summary

The laboratory of Dr. Brian Gordon (https://sites.wustl.edu/gordonlab/) is recruiting a postdoctoral fellow to join the Neuroimaging Labs Research Center (NIL-RC) based in Mallinckrodt Institute of Radiology at Washington University in St. Louis. The fellow will join NIH-funded projects to understand longitudinal brain-behavior associations in individuals with both sporadic and autosomal dominant Alzheimer disease (AD). These cohorts are deeply phenotyped and include PET (amyloid and tau), biofluid (CSF and plasma), MRI, and neuropsychological testing. Researchers will have the opportunity to collaborate with other world class faculty in the NIL-RC, as well as at the Charles F. and Joanne Knight Alzheimer Disease Research Center.

Given the richness of the available data, the focus of the position will be tailored to the postdoc’s particular interests and strengths.

Some current projects of emphasis in the lab are:
1. Cross-modal study of biomarkers (e.g. tau PET and CSF ptau181, ptau217, and ptau205).
2. Comparison and validation of multiple tau PET tracers (Flortaucipir and MK-6240).
3. Predicting the spread of pathology using connectivity derived from DTI and resting state fMRI.
4. Understanding how pre-clinical pathology erroneously contributes to estimates of “normal” aging.
5. Exploring differences between sporadic and autosomal dominant forms of AD.