Posted: 8/8/2023

Postdoctoral Research Associate (BMRC, Guglielmetti Lab)

The Washington University School of Medicine, Mallinckrodt Institute of Radiology has an opening for a postdoctoral research associate to join the Biomedical MR Center (BMRC). The successful candidate will be involved in projects to develop and characterize new metabolic imaging approaches to monitor neuroinflammation, neurodegeneration, and response to novel therapies. There is a particular emphasis on the development of hyperpolarized 13C magnetic resonance spectroscopy in combination with PET/CT imaging in preclinical models of Multiple Sclerosis and other neurodegenerative diseases. Overall, this research aims to generate an improved mechanistic understanding of the highly complex interplay between the immune system and brain health, as well as set the stage for clinical translation of novel imaging methods.

The successful candidate will develop expertise in metabolic imaging of preclinical models of neurological disorders. The candidate will be expected to lead research projects, publish in leading scientific journals and conferences. The postdoctoral research associate will participate in set-up of project proposals and participate in funding activities. The candidate will be strongly encouraged and supported to develop career skills, including writing, public speaking, networking, and applying for independent fellowships and grants. Training will be provided in disciplines with which the candidate is less familiar.

Information on being a postdoc at Washington University in St. Louis can be found at

Learn More and Apply

Required Qualifications
• Ph.D. in Neuroimaging, Biomedical Sciences, Neurosciences, Immunology or a related field, with an emphasis on brain research
• Knowledgeable within one or more of the following subjects: MRI, PET/CT imaging, MR spectroscopy (MRS), hyperpolarized 13C MRS, MR sequence programming, metabolism, immunology, neurological disorders.
• Ability to clearly communicate research findings through oral presentation and written publication.
• Ability to work independently and in a collaborative manner with a diverse group of scientists and clinicians.

Preferred Qualifications
• Experience with small animal imaging (MRI, PET/CT) and data analysis.
• Experience with data analysis, post-processing, and statistical analyses using Excel, MATLAB, SPSS, Python, or related software.
• Experience with preclinical models of neurological disorders, including handling of research animals.
• Experience with quantitative analyses of tissue (immunofluorescence analyses, activity assays, western blots, flow cytometry).

Working Conditions
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range
Base pay is commensurate with experience.

Applicant Special Instructions
Interested candidates are encouraged to email a CV, a cover letter describing research interests and previous experience, and references to Dr. Caroline Guglielmetti.