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Like all great cities, St. Louis comprises many distinct neighborhoods, each with a unique history, character and style. A few of these are described below, but the list is by no means all-inclusive.

St. Louis’ Central West End, home to Washington University School of Medicine, is an area populated with cafes, galleries, boutiques, pubs, and restaurants. Noted to have a distinct European feel, its architecture includes tree-lined streets and turn-of-the-century homes, as well as the Cathedral Basilica of Saint Louis. Among its many cultural offerings are the World Chess Hall of Fame and the annual Labor Day Festival hosted by the St. Nicholas Greek Orthodox Church. Other annual events include a spring house tour, the Central West End Art Fair & Taste Festival in June, and Halloween festivities in October.

University City, one of the older suburbs in the St. Louis area, is home to the Delmar Loop, an entertainment, cultural, retail, and restaurant district popular with denizens of Washington University and located just a few blocks to the west of its Danforth Campus. Delmar Boulevard’s St. Louis Walk of Fame honors famous St. Louisans, and the Delmar Loop Trolley, slated to begin operation in late 2014, will have stops at 10 stations on a 2.2-mile route, including Washington University, the Missouri History Museum in Forest Park, and two MetroLink stations. University City also is home to COCA, a center for contemporary arts that has a nationally recognized pre-professional dance training program, as well as many other popular cultural institutions. The University City Olive Link is known for its high concentration of East Asian business, as is considered the replacement for St. Louis’ original Chinatown. In 2007, the Delmar Loop was named one of the "10 Great Streets in America" by the American Planning Association.

Soulard, a historic French neighborhood in a historically French city, hosts many popular events throughout the year, including the largest Mardi Gras celebration in the Midwest each spring, and Oktoberfest, a popular annual fall festival. A residential area filled with restaurants,pubs, and other businesses, Soulard is one of the oldest communities in St. Louis. Its unique architecture includes homes and churches that date back to the mid-19th century, as well as the North American headquarters of Anheuser-Busch. Soulard also is home to the oldest Farmers Market west of the Mississippi, with more than 100 vendors offering produce, meat, spices, flowers and food four days a week.

The Hill, a mostly Italian-American neighborhood, is located on high ground (hence, its name) just south of Forest Park and Washington University School of Medicine. An area settled by Italian immigrants beginning in the late 19th century, the Hill today boasts a variety of restaurants, bakeries, grocery stores, pubs, and two bocce gardens. Its St. Ambrose Catholic Church, modeled after Sant’Ambrogio Church in Milan, Italy, is a landmark in the community, which counts baseball greats Yogi Berra and Joe Garagiola among its native sons.


Just south of downtown St. Louis, historical Cherokee Antique Row offers six blocks of antique and specialty shops, art galleries, and restaurants, including a variety of Mexican eateries.

Clayton, the financial and business district for St. Louis County, is adjacent to Washington University's Danforth Campus. A lovely residential area, Clatyon offers a variety of restaurants, galleries, and shops, and hosts a number of special events throughout the year, including Parties in the Park, an after-work party with live music in downtown Clayton, and the annual St. Louis Art Fair in September.

Since 2000, more than $5 billion has been invested in Downtown St. Louis, spurring a dramatic turnaround that has re-established downtown as the heart and soul of the St. Louis region. A hub for businesses and jobs, Downtown St. Louis also offers the best in cultural arts, outdoor recreation, children's attractions, restaurants, and retails stores. In 2010, a downtown trolley was established to enable tourists to more easily travel between attractions, sports venues, culture, and retail and dining establishments.

Nearly one million people live in St. Louis County, which surrounds the city to the sis divided into four sections: West County, Mid County, North County, and South County...

Explore St. Louis Neighborhoods offers details on additional locales.