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Daniel S. Marcus, PhD
Research Assistant Professor
Department of Radiology
Department of Psychology

1994: Washington University in St. Louis, BA-Biology/English Literature
2001: Washington University in St. Louis, PhD-Neuroscience


Marcus DS, Olsen T, Ramaratnam M, Buckner, RL. The extensible neuroimaging archive toolkit (XNAT): An informatics platform for managing, exploring, and sharing neuroimaging data. Neuroinformatics. 2007;5:11-34.


Marcus DS, Archie KA, Olsen T, Ramaratnam M. The open source neuroimaging research enterprise. J Digital Imaging. 2007;20(suppl 1):130-138.


Keator DB, Grethe JS, Marcus D, et al. Function BIRN, Morphometry BIRN, BIRN Coordinating Center. A national human neuroimaging collaboratory enabled by the Biomedical Informatics Research Network (BIRN).  IEEE Trans Info Tech Biomed. 2007;12:162-172.


Marcus DS, Wang T, Buckner RL. Open Access Structural Imaging Series (OASIS): Cross-sectional MRI data in young, middle aged, nondemented and demented older adults. J Cogn Neurosci. 2007;19:1-10.


Burns JM, Church JA, Johnson DK, et al. White matter lesions are prevalent but differentially relate to cognition in aging and early AD. Arch Neurol. 2005;62:1870-1876.

Research Description
Dr. Marcus' interests cover a broad range of medical informatics and neuroinformatics issues, including databases, data sharing, data mining, image visualization, and ontology.

His research group has developed XNAT (www.xnat.org), an open source software application designed to manage, analyze, and share neuroimaging and related data. XNAT is being used to support a number of projects at Washington University in St. Louis (including studies of Alzheimer's Disease, ADHD, and healthy brain aging) and at many other institutions across the country. Current efforts are geared toward connecting multiple XNAT sites into a single virtual entity. A long-term goal is to build a national neuroimaging database infrastructure that enables collaboration and knowledge discovery. Along these lines, Dr. Marcus' group is a contributing member of the Biomedical Informatics Research Network (BIRN), an NIH-supported organization that is building technical solutions to these informatics challenges, and the National Alliance for Medical Imaging Computing (NA-MIC).

East Building
4525 Scott Avenue
Campus Box 8225
Phone: (314) 362-4562
Fax: (314) 362-6110
E-mail: dmarcus@wustl.edu

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